The Parkinson’s Progression Markers Initiative: How does Parkinson’s start and change?

Researchers around the world aim to identify how Parkinson’s starts and changes over time. This will ultimately help to develop new treatments, better clinical care, and potentially prevent Parkinson's.

Who

People who meet the criteria of one of the following groups may be eligible to participate:

• People with Parkinson’s who are over 30 years old and have been diagnosed with Parkinson's in the last 7 years. This can include people who are or aren’t taking medication or intervention for Parkinson's symptoms (including DBS)

• People without Parkinson’s who are over 40 years old. The researchers are especially interested in hearing from people with REM Sleep Behavior Disorder

What

Initially, you will be asked to visit the research site to discuss the opportunity and see if you are eligible to take part.

The study will then monitor you over a number of years, where you will be required to attend 4 study visits in the first year and 2 visits in the second year. At each visit, you will complete different assessments such as physical and neurological exams, memory tests and brain scans.

Once you are enrolled in the study you will receive compensation for each research visit, and travel costs related to the study will be reimbursed up to a reasonable amount.

For detailed inclusion criteria, please visit the Study Cohorts page of the research website.

Interested in taking part?

Please read the Participant Information sheet, then scroll down to find your nearest study site, click the arrow, and contact the relevant research team.

The deadline for this research is 31 December 2026.

If you have any further questions, please contact [email protected].

Deadline

31 December 2026