Ronnie taking his medication

March update on Sinemet availability


In January we updated you that some Sinemet products might be unavailable due to a manufacturing issue.

We continue to receive regular updates from Merck Sharp & Dohme Limited (MSD), who manufacture the medication, to hear about the supply issues and action they're taking to ensure Sinemet is available for people with Parkinson's across the UK.

MSD have shared with us that they have managed to keep the majority of Sinemet products in stock.

However, there are 2 products that are likely to be unavailable from mid-March:

  • Sinemet 25/250mg 10x10 tablets – unavailable from mid-March to early May.
  • Sinemet plus 10/100mg 10x10 tablets – unavailable from mid-March to mid-May.

MSD confirmed that these Sinemet products are all available:

  • Sinemet 12.5/50mg 9x10 tablets.
  • Sinemet Plus 25/100mg 10x10 tablets.
  • Sinemet Half CR 25/100mg 6x10 tablets.
  • Sinemet CR 50/200mg 6x10 tablets.

We will continue to share further updates on Sinemet availability as we receive them.

Will this affect me?

If you take Sinemet 25/250mg or Sinemet plus 10/100mg your pharmacist may be unable to give you your prescription.

However, there are generic versions of Co-careldopa, the active ingredient in Sinemet, available in a range of strengths.

Your GP or pharmacist can discuss this with you and should be able to offer you a suitable alternative.

A statement from MSD says:

"The delay in the resupply for the above Sinemet products is due to current manufacturing capacity constraints.

"Patients who may be affected by this shortage should contact their healthcare professional or pharmacist to discuss their treatment options.

"As we receive updates from manufacturing we will keep Parkinson's UK informed."

Angela, who works for the helpline, answering a phone call

Get support

If you have any questions or concerns regarding your medication, or if you're unable to obtain Sinemet, you can discuss this with your GP, consultant, pharmacist or Parkinson's nurse.

You can also contact our helpline on 0808 800 0303.

More about our helpline and local advisers